Leukemia: Treatment


Western medicineTCMToday , there have been updated and more effective treatment methods introduced , a lot of people can be cured of leukemia , and abundant life. Doctors will first leukemia types according to whether there is metastasis, have previously suffering from other cancers, patient age , presenting symptoms and general physical condition , etc., designed for each specific leukemia treatment plan .
Although the condition is more dangerous acute leukemia , chronic leukemia, but easier than cure . Acute leukemia is usually white blood cells to kill disease -based and make no recurrence , and most doctors will treat asymptomatic after five years for the cure fiducial marks . Chronic leukemia cure rate is low, the main purpose is to delay treatment of disease progression and control symptoms . The standard treatment of adult leukemia is chemical treatment and bone marrow transplant therapy, a special type of leukemia will use radiation therapy and immunotherapy . Because leukemia will spread the body, it can not be treated with surgery , but some cases require surgical assistance, such as the spleen swelling is too large , the doctor will conduct splenectomy .
RadiotherapyUsing X -rays or other high- energy beam irradiation or certain parts of the body to kill leukemia cancer cells. This method is usually used to have invaded the central nervous system leukemia, or leukemia have been transferred to the bone and testicles , where can relieve pain .
ImmunotherapyUsing the body's own antibodies or proteins made ​​in the laboratory , improve , or restore the body to fight disease boot function . Such as the application α interferon enhance immune function, and may slow down of chronic myelogenous leukemia (CML) progress .

ChemotherapyIs the most commonly used method, using one or more chemical drugs to oral or intravenous route to kill cancer cells , also known as systemic chemotherapy. Too few anticancer drugs acting on DNA or genetic material within cells , and cancer cells, these substances are very active , so by the main impact .
General treatment of acute leukemia in three steps:1 remission induction ;2 . Remission after treatment ;3 Treatment of relapse
In addition , acute lymphoblastic leukemia (ALL) required to undergo brain preventive treatment of leukemia .
1 remission induction
Induction chemotherapy is started anticancer therapy, or arising " complete remission ," " complete remission " means that the patient's leukemia symptoms have completely disappeared, and the blood and bone marrow basically back to normal. The purpose of this treatment is to try to produce leukemia cells divide, so back to normal hematopoietic function of bone marrow . The response rate in patients dependent on many factors, such as patients receiving intensive treatment tolerance , age and medication selection.
Acute myelogenous leukemia (AML), chemotherapy typically include "cytarabine" and one of "anthracycline" drugs such as "daunorubicin", "mitoxaanthrone" or "idarubicin" the joint use . This program allows patients response rate 60-80%. However, in acute promyelocytic leukemia (APL) to the exception , the patient's body as retinoic acid ( vitamin A one kinds ) receptor defects, bone marrow cells prior to bone marrow is not a mature leukocytes . A vitamin A derivative "Tretinoin" requires additional chemotherapy programs to enable leukemia cells to mature and die. Also used in this type of leukemia drug arsenic.
 

Acute lymphoblastic leukemia (ALL), commonly used anticancer drugs Changchun new , arsenic , phosphorus  ring amines, amine aspartic  enzymes and prednisone .
 

Chronic myelogenous leukemia (CML), the general use of urea alcohol or interferon , a new oral drug "Gleevec", in a clinical trial of patients can be successfully induced cause remission.
 

Chronic lymphocytic leukemia (CLL), commonly chlorambucil , "fludarabine" and cyclophosphamide  amines. Chlorambucil make 48% of the patients had 5-year survival , but long-term use will fail .2 . Remission after treatment
When the leukemia into remission and successful induction therapy from adverse reactions to recover , it will begin this phase of treatment to kill residual cancer cells. If you do not consolidate and strengthen the treatment, most patients will relapse, so you must continue to use these drugs , but the drug regimen or dose modification as appropriate .
Acute myelogenous leukemia (AML), high-dose "cytarabine" commonly used in patients over 55 years of age , so that long-term illness release 15 to 50% survival rate .
 

Acute lymphoblastic leukemia (ALL), but the technique is still used chemotherapy dose will be reduced. Typical solutions include continuous low-dose oral methotrexate , and 6 - mercaptopurine , it may take several years of continuous use .3 Treatment of relapse
" Relapse " refers to the leukemia cells in the blood and bone marrow appears again inside . This period of response to chemotherapy treatment before remission than poor . If a suitable donor can choose a bone marrow transplant and improve survival .
4 Brain leukemia
Certain types of leukemia are particularly vulnerable to violations of the central nervous system , such as to the prevention or treatment , the doctor will inject drugs to the brain and spinal cord cavity to kill cancer cells. This method , also known as intrathecal therapy , usually with radiation therapy or high-dose systemic chemotherapy simultaneously.
Bone marrow transplant (BMT): is the best treatment for some patients , usually in remission but there is a high chance of recurrence in patients not adequately or commonly used treatment response or relapse after treatment . The surgery will take first with total body irradiation or intense immunosuppressive drugs , effectively rid leukemia cells, while normal white blood cells to kill the bone marrow . Then with similar or identical leukemia beginning of normal bone marrow progenitor cells , injected or transplanted into the patient's blood in the hope that these transplanted bone marrow cells can be new again to manufacture healthy white blood cells .
Autologous bone marrow transplantation :
 
With the patient's own healthy bone marrow cells into the damaged bone marrow cavity .
 

Allogeneic bone marrow transplantation :
 
To the health of the donor bone marrow cells injected into the patient's bone marrow cavity . Donor bone marrow cells and patient needs in all six cell markers coincide, cell markers , also known as human leukocyte antigens (HLA), they may be the patient's twin children or HLA-identical siblings . Recently , HLA mismatch healthy bone marrow cells may also be transplanted .
According to most observed in clinical trials of two identical survival after transplantation . Transplant surgery after two years , approximately 50% of patients successfully . Transplant surgery itself higher recurrence rate may be due to not completely remove all cancerous cells . But there are more deaths allogeneic transplant surgery , mainly due to complications.
Complications of treatment
Chemotherapy complicationsComplications of bone marrow transplantationNew therapiesScientists and doctors have developed regularly updated and more effective treatment methods , mainly concentrated in certain areas , such as raising the effectiveness of conventional medication , reduce side effects , or to try new ways to attack leukemia cells. This chapter comes with a number of ongoing treatment studies , the most common and effective in clinical trials .
Click here to refer to the latest therapies
Secondary or alternative therapyIn the U.S., more and more people recognize or apply vitamin and herbal products . These products are usually grouped into healthy food categories, conventional anti-cancer therapies can relieve adverse reactions helpful . But not yet in-depth study clearly substantial benefits and harm. Therefore the use of such therapy , should discuss with your doctor first and make many different perspectives . These products are now being carried out scientific research in the United States National Health Service or agency will also plan to test these products .

 
TCM mainly by their Differentiation and Treatment :
1 damp-
Treatment goals :
 
Because heat Evils covered the body, so the main objective is to heat and dampness , and resolve toxins.
Prescription Example:
 
Chaiqin Chen Ling decoction
Bupleurum , Scutellaria, gentian , gardenia , orange peel, Poria, Pinellia, Alisma, Polyporus , Atractylodes, reed rhizome, snake tongue grass , indigo .

(2) Heat -toxin
Treatment goals :
 
Mainly as toxic heat flaming, camp blood disturbed symptoms, it should detoxification, cooling bleeding.
Prescription Example:
 
Huang Decoction buffalo horn
Buffalo horn , habitat , Dan, red peony , honeysuckle , forsythia , gardenia , gypsum, diffusa . Such as hot even coma , could swallow Zixue , treasure Dan or Angongniuhuang .

3 disease product type
Treatment goals :
 
Mainly due to stasis phlegm obstruction due to road networks , it should Treating Endometriosis based.
Prescription Example:
 
Taohongsiwu decoctionPeach kernel , safflower, Chuanxiong , Angelica , to yellow , red peony, seaweed, turtle shell , raw oysters, Fritillaria , Prunella .
4 liver wind type
Treatment goals :
 
This type of condition is most critical , so to aromatic resuscitation , first aid Pingganxifeng of the law .
Prescription Example:
 
Zhenganxifeng soupHuai Achyranthes, Health keel , raw white peony , aspartame , raw malt, Ruddle , raw oysters , Scrophulariaceae, Toosendan , tarragon , turtle shell , licorice .
Also can be brewed into tea Zixue Dan, Angongniuhuang .
5 Yin Deficiency type
Treatment goals :
 
This type of heat toxin hurt consumption of gas, burns really overcast , so the treatment is mainly to Qi Yang Xin , Yin and kidney .
Prescription Example:
 
Shengmai , two to co- Huang DecoctionLittoralis, Ophiopogon , Schisandra, Ligustrum lucidum, Eclipta , medlar, habitat, Dan , Poria , Coix Seed , Tribulus terrestris , turtle shell .
Also you can add snake tongue grass, half-sticks lotus clear vestiges .
6 qi and blood loss type
Treatment goals :
 
This type is mainly manifested as qi and blood loss , TCM believes that the spleen is acquired, the kidney is the innate, two dirty are the source of qi and blood biochemistry , so this type of treatment is mainly Qi and blood, spleen and kidney .
Prescription Example:
 
Jun Dangguibuxuetang and four , eight decoctionAstragalus , Codonopsis , Angelica , Atractylodes , Poria, Rehmannia , wolfberries , Ligustrum lucidum, gelatin .
In addition to compatibility diffusa , thistle , etc. to clear more than evil , secure small collaterals .

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